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This approach has proven effective in various national contexts, demonstrating that clear understanding between health and other policy areas leads to more proactive health prevention measures (Patel et al., 2021)

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That may be a rational design for local GI exposure , where systemic bioavailability may not even be the primary objective

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However, they might occur depending on the dose and the patients current health condition

Alfayez M, Kantarjian H, Ravandi F, Konopleva M, Jabbour E, Garcia-Manero G, Kadia T, Borthakur G, DiNardo C, Estrov Z, Pemmaraju N, Pierce S, Yilmaz M, Short N, Takahashi K, Assi R, Andreeff M , Cortes JE, Daver N