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[7] The protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell death and increases resistance to toxic challenges, especially oxidative stress

Upon stimulation of the cells, the polyunsaturated fatty acid arachidonate (20:4n-6) is released from the cell membrane by phospholipase A2

Fears, T

10.1016/j.neulet.2013.12.011 309 YamaguchiS.MeguroK.ItohM.HayasakaC.ShimadaM.YamazakiH.et al (1997)

Treatment selection depends on the specific autoimmune condition and disease severity

Moreover, many studies were performed to explore the deeper mechanism