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Is the treatment painful

The authors RC and FP declared that they were an editorial board member of Frontiers at the time of submission

Research-Referenced Functional Attributes (Based on existing preclinical and literature datanot intended as claims of therapeutic use) High-affinity binding to HGF and potentiation of c-Met activation in the presence of subthreshold HGF concentrations in cellular assays (DOI: 10.1124/jpet.114.218735) Induction of synaptogenesis and dendritic spine formation through HGF/c-Met pathway augmentation in neuronal models Observation of PI3K/AKT signaling modulation in APP/PS1 mouse models (DOI: 10.3389/fnagi.2021.748253) Investigation of neuroregenerative signaling mechanisms in scopolamine-induced impairment paradigms Examination of synaptic protein expression markers in aging or stress-challenged experimental systems Examination of oral bioavailability and blood-brain barrier penetration in rodent studies

Shen B, Yi X, Sun Y, Bi X, Du J, Zhang C, et al

We monitor patients regularly and adjust protocols based on response

Hero molecule emphasis: PDRN (MITF downregulation, anti-melanogenesis), GHK-Cu (dermal remodeling), Centella (post-procedure barrier protection in pigment-sensitive skin)