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Common Mild Side Effects Short-term redness or slight irritation at the injection site Light water retention, especially during the initial weeks Increased appetite Mild headaches (rare and usually transient) Temporary fatigue or lightheadedness immediately after injection Who Should Avoid This Therapy People with an active cancer diagnosis or history of cancer, as GH secretagogues increase cellular replication rates Pregnant or breastfeeding individuals should avoid this therapy due to insufficient safety data on its effects during these stages

"But the latest randomized controlled data and updated guidelines now support a more personalized strategy." The initial caution stemmed from concerns about delayed gastric emptying, a known side effect of GLP-1 receptor agonists such as semaglutide and tirzepatide

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