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Archived from the original on 2009-03-20

This is supported by studies using neurons differentiated from patient-derived induced pluripotent stem cells (iPSC), which were found to display hyperexcitability and increased intracellular Ca 2+ levels, as well as increased transcription of genes involved in Ca 2+ -signalling, compared with neurons derived from healthy unaffected controls [19, 20]

S., Earl, H

Patients should be advised that replacing vitamin B 12 folic acid, which could cause a progressive subacute combined degeneration

Nausea, constipation, and decreased appetite are most common, particularly during dose titration

However, there is limited clinical experience with dulaglutide in liver disease so caution should be used