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GLP-1 and gastric inhibitory polypeptide (GIP) are two incretin hormones, which stimulate postprandial insulin secretion (88)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Semaglutide and cardiovascular outcomes in obesity without diabetes

Timing the increase for the follicular phase (days 1 through 14 of the cycle) can reduce the overlap between hormonal GI effects and dose-escalation GI effects

They are also expressed in other tissues, such as blood vessels or adipose tissue29,30 although their localization in different tissues and organs yields discrepant results.31 GLP-1 or its agonists slow gastric emptying

JAMA Intern Med 2022;182:513-9.ArticlePubMedPMC 40