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It was also important to compare results for the 2F8A human model with those of another structure-based model of GPx1 given that the selenocysteine in the active site of 2F8A is mutated to glycine which may affect the binding poses of ligands predicted by the model

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Hubbard SR, Hendrickson WA, Lambright DG, Boxer SG

Ohtsu, E., Ichiyama, A., Nishizuka, Y

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From a technical perspective, we needed to seamlessly integrate the experience with a new check capture SDK, which posed potential complexities and challenges for the team