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The discovery of additional pockets on the target enzyme, target optimization (identifying substitutable targets), and the use of computational tools may offer new strategies

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It is a glucagon-like peptide-1 (GLP-1) receptor agonist that works by stimulating insulin secretion when blood glucose levels are elevated, suppressing glucagon release, and slowing gastric emptying

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This is the rationale behind topical and oral use for eczema, psoriasis, and dermatitis, though dedicated human trials for those conditions are not there yet