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Studi Mengenai Bahan Pencerah Kulit Journal of Cosmetic Dermatology menerbitkan studi yang menjelaskan bahwa penggunaan topikal Niacinamide (Vitamin B3) terbukti secara signifikan mengurangi hiperpigmentasi dan meningkatkan kecerahan kulit dalam waktu 4 minggu penggunaan rutin