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Elevated growth hormone levels, even when stimulated endogenously via sermorelin, can promote insulin resistance over time

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While both compounds work through different mechanisms that theoretically could complement each other, the safety, efficacy, and optimal dosing of this combination remain completely unknown

Lean tissue accounted for approximately 39% of total weight lost (Wilding et al., NEJM , 2021)

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Additionally, individuals with a recent history of serious conditions such as pancreatitis, thyroid cancer, or other exclusions specific to the study may not qualify