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Although the patients body weight temporarily decreased from 92.4 kg to 90.8 kg during the first 3 months of treatment, it returned to 92.0 kg over the following 6 months ( Supplementary Figure 1 )

Finally, individual response to side effects varies considerably

Whether its for medical treatments, prescription medications, or specialized care, knowing how to effectively appeal a denial of coverage can provide peace of mind and access to necessary healthcare services

Dosing progression matters: slow titration (2.5 mg weekly, then 5 mg, then 7.5 mg, then 10 mg) extends the timeline but improves tolerability

From day 4 onwards, the dose should be titrated to the usual effective dose of 300 to 450 mg/day

Energy for early mobilisation is lower