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Research data indicates that the alteration in FOXO proteins may contribute to the disease etiology[6]

We showed that haem-mediated dimerization of PGRMC1 enhances proliferation and chemoresistance of cancer cells through binding to and regulating EGFR and cytochromes P450 (illustrated in Fig

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Compared with conventional formulations, NPs can provide more controlled drug release, and higher delivery precision, which may increase bioavailability and prolonged therapeutic exposure [19, 20]

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