The GlyNAC protocol (NAC + glycine) alone has been shown to restore glutathione to youthful levels in older adults within 2-4 weeks
It binds to the ghrelin/GHS receptor on pituitary cells, stimulating growth hormone release
If it is true rejuvenation there should be an increase in lifespan as well, and there is no mention of increased lifespan or whether that was even investigated
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J Nephropharmacol 5(1):4956 Kodera R, Shikata K, Kataoka HU, Takatsuka T, Miyamoto S, Sasaki M et al (2011) Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes
View Study Schuttelaar MLA, Coenraads PJ