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Systemic injection (into abdominal fat or another convenient site) allows the peptide to distribute throughout the body and migrate to damaged areas

Medications with narrow therapeutic windows (thyroid hormones, anticoagulants, certain antibiotics) may be absorbed differently when gastric emptying is slowed

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Using a range of amide-containing probe compounds (0.510 M), we have investigated the hydrolytic activity of several rat, minipig and human-derived in vitro systems - including Supersomes, microsomes, S9 fractions and hepatocytes - with respect to their previously observed human in vivo metabolism

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