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4.4 Long-term safety and off-target effects Emerging reports link GLP-1RAs to rare ocular adverse events, including NAION ( 5 Conclusion In conclusion, the expanding body of evidence supports that GLP-1RAs offer a multifaceted approach to ocular therapeutics by targeting key molecular pathways involved in retinal neuroprotection, mitochondrial regulation, inflammation, vascular remodeling, and angiogenesis

doi: 10.1007/s00394-017-1445-8 Summary Keywords antioxidant, bioavailability, biological properties, immunological properties, polyphenols Citation Saad AM, Mohammed DM, Alkafaas SS, Ghosh S, Negm SH, Salem HM, Fahmy MA, Semary HE, Ibrahim EH, AbuQamar SF, El-Tarabily KA and El-Saadony MT (2025) Dietary polyphenols and human health: sources, biological activities, nutritional and immunological aspects, and bioavailability a comprehensive review

902 Due to the increased demand for iron in osteoclast development, TFR1-mediated iron uptake promotes osteoclast differentiation and bone resorption activity

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The gap in their results tells the whole story

Acierno C, Barletta F, Nevola R, et al