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Osmolality Tonicity Assessment Nasal sprays should be formulated as isotonic solutions (270330 mOsm/kg) to minimize irritation and damage to the nasal mucociliary clearance apparatus

Introduction Dengue virus is a major mosquito-borne disease worldwide, with a thirty-fold increase in incidence during the past 50 years [1]

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10.1038/nature05487 111 VertuaniS.AngustiA.ManfrediniS

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Future research priorities include understanding the long-term effects of senescent cell elimination on tissue homeostasis, regenerative capacity, and overall healthspan, providing foundation for developing sophisticated approaches to aging research and intervention strategies