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This is an early signal that demand for a pill formulation is very real in a space that has been dominated by injections

Tirzepatide works by activating both GLP-1 and GIP receptors, which dramatically reduces appetite

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Many patients also lose weight because GLP-1 medicines reduce appetite and slow digestion

Boosts Energy & Focus Even mild dehydration can cause fatigue and brain fog symptoms that can mimic GLP-1 tiredness. Regulates Digestion Adequate fluid intake softens stool, prevents constipation, and promotes smoother digestion

One study found that in NRXN1 +/- human induced pluripotent stem cell (hiPSC)-derived neurons, there was a significant increase in expression of novel NRXN isoforms, coupled with a decrease in the wild-type NRXN isoform [179]