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Hostin revealed that her weight gain triggered fluctuations in her cholesterol, causing it to shoot up to 200

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The initiation of insulin is recommended when severe hyperglycemia (more than 9% HbA1c) is detected at diagnosis, especially if hyperglycemic symptoms (polyuria or polydipsia) or any catabolic features (weight loss or ketosis) are present

Further, positive feelings about real or potential weight loss with tirzepatide may have contributed to the observed improvement in psychiatric symptoms

Type 2 diabetes in adults: management (NG28) summary of medicines recommendations

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