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Seizure-induced oxidative stress in temporal lobe epilepsy

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The use of GLP-1/glucagon chimaeric ligands, coupled with site-directed mutagenesis of the glucagon receptor, has shown that the reduced activity of an analogue of glucagon, with Ala at position 2, could be rescued by mutating Asp 385 to Glu, suggesting that the N-terminus binds close to the TM7/ECL3 boundary (Runge et al

Cre-dependent DREADD (Designer receptors exclusively activated by designer drugs) mice

MGMT inhibition in ER positive breast cancer leads to CDC2, TOP2A, AURKB, CDC20, KIF20A, Cyclin A2, Cyclin B2, Cyclin D1, ER and Survivin inhibition and enhances response to temozolomide

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