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Clinical Benefits: Supports cellular energy production via the Krebs cycle and mitochondrial function Assists in the metabolism of carbohydrates, fats, and proteins Supports peripheral and central nervous system function Provides antioxidant protection against oxidative stress Supports immune function and recovery from illness May help address fatigue, low mood, and cognitive difficulties This combination is often recommended as part of a broader treatment plan for patients with chronic fatigue, nutritional deficiencies, or those who are not responding adequately to oral supplementation alone

However, the beneficial effects of KD on NAFLD have been widely reported

doi: 10.1016/j.bbagen.2012.11.020 16

The incretins have far stronger and more mature human clinical data

2006 Apr;97 Suppl 1:82-6

Folate Receptor Autoantibodies (FRAAs) in ASD A larger percentage of children with ASD have been found to have autoantibodies against the folate receptor alpha (FR) , which impair folate transport across the blood-brain barrier (BBB)