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It has been reported that cellular uptake of glutamine and its subsequent efflux in the presence of essential amino acids, including leucine, is the rate-determining step that activates mTORC1 191

doi: 10.1016/j.pnpbp.2022.110518

doi: 10.1093/ecco-jcc/jjw074 168 WangY.XieQ.ZhangY.MaW.NingK.XiangJ