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When glutathione, the master intracellular antioxidant, declines, oxidative stress accumulates in skin cells first
Lancet 354 , 456460 (1999)
10.1016/j.carbpol.2025.124074 186 ZhangX
It is also possible that damage via the carbonyl stress pathway may only occur at a local level limited to renal tissue
Additionally, glutathione added directly to the bloodstream is only active for a short time , so it may not be effective for consistently raising GSH levels over time
Thus, despite stimulated glycolysis, glucose oxidation is noticeably declined in taurine-deficient hearts, which intensely reduces the contribution of glucose metabolism toward overall adenosine triphosphate (ATP) biosynthesis
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