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In contrast, vehicle-treated MIA mice showed no significant change in their sociability scores

Arans C, Edvardsson CE, Shevchouk OT, Zhang Q, Witley S, Blid Skldheden S, et al

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For example, activation of the hypothalamuspituitaryadrenal (HPA) axis by cytokines (e.g., IL-1 and IL-6) triggers synthesis and release of glucocorticoids with potent immunosuppressor effects [42]