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In the Phase 2 study the highest arm continued upward toward higher maintenance targets, but the core principle held throughout: escalate only after the current step is tolerated , in roughly four-week increments

Data are a representative example of eight independent experiments for which summary statistics are mean (SD): pK B 5.14 (0.2) and log 2.64 (0.4)

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Patients who attempt to skip stages or increase amounts independently may experience more pronounced digestive discomfort or other reactions than those who follow a provider-guided pace

If nausea or vomiting is severe or persistent, contact your GP or diabetes specialist nurse

Metabolism: Clinical and Experimental