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Effect on body weight This is perhaps the most dramatic difference

They were not worse off than they were before," Aronne said, "And in some cases, they were significantly better than where they started

Individual responses vary considerably, and some patients may experience minimal appetite changes despite therapeutic dosing

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Perhaps even more meaningful than mean weight loss is that most patients who were randomly assigned to the drug were able to achieve 10%, 15% and 20% benchmarks for weight reduction

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