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Additionally, the Effect of Sotagliflozin on Cardiovascular Events in Patients With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF) trial showed that, in people with type 2 diabetes and worsening HF, sotagliflozin reduced the total number of cardiovascular deaths or hospitalisations or urgent visits for HF compared with placebo regardless of ejection fraction [150]

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Target outcomes at 6 months: BFM reduced by 35 kg, SMM stable or improved, VFL reduced by 2 levels, BMR within 100 kcal of baseline, Phase Angle stable or improved