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Side Effects: Gastrointestinal side effects, such as nausea, are common initially but can be managed by gradually adjusting the dosage

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It has potent effects on blood glucose by either stimulating glucose-induced insulin release or inhibiting glucagon secretion [8, 9], and suppresses appetite via receptors in the ventral tegmental area, the nucleus accumbens and the hypothalamus (Fig

That is how muscle loss and fatigue creep in

doi:10.1007/s12011-012-9462-1