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4 PD complications and comorbidities Recent epidemiological surveys have refined our understanding of comorbidity patterns in PD

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Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX), a producer of reactive oxygen species (ROS), acts as a key generator of oxidative stress within pancreatic islet -cells, significantly affecting glucose-induced insulin release and -cell viability in Type 1 and Type 2 diabetes (Eloisa Aparecida et al., 2021)

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Glucagon-like peptide-1(137) inhibits chemokine-induced migration of human CD4-positive lymphocytes