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In this 52-week trial of 1,698 people with type 2 diabetes whose blood sugar wasn't adequately controlled on Metformin, orforglipron outperformed oral semaglutide on every primary and secondary endpoint, including A1C reduction and weight loss, with improvements visible as early as four weeks

The data reveal meaningful differences between compounds, and understanding these differences can inform conversations with your healthcare provider about medication selection if hair loss is a significant concern for you

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A patient with Type 2 diabetes choosing between a GLP-1 and an older oral agent is no longer making a purely glycemic decision

doi: 10.20517/cdr.2018.004 103 Ruiz-RodadoVLitaADowdyTCelikuOSaldanaACWangHet al

The AIP (aryl hydrocarbon receptor-interacting protein) gene and its relation to the pathogenesis of pituitary adenomas