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Human intestinal microbiota: characterization of a simplified and stable gnotobiotic rat model

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It can also increase the risk of gastrointestinal infections like Salmonella and Campylobacter

It is shallow, so the needle only travels a short distance, and it has fewer pain-sensitive nerves than deeper tissue, so most people feel a small pinch rather than a deep ache

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If sensitivity emerges, we pause or step back, address likely antigenic drivers (e.g., dairy in FRAA-positive cases), and consider gentler supportive measures before resuming