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Animal models: Nanoliposome-encapsulated GHK-Cu showed accelerated hair growth in C57BL/6 mice with visibly earlier anagen onset compared to free peptide controls (Tian et al., 2022)
The difference between 10mg and 15mg was relatively small (about 1 percentage point), which is why many people find their effective maintenance dose in the 7.5mg to 10mg range without needing to push to maximum
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Alternating phases allows pathways to reset and may help maintain effectiveness over time
This may indicate a possible re-establishment of nitrogen balance, and a potential modification or enhancement of nitrogen levels in different tissues