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Signaling observed in cell cultures or animal models does not automatically translate into predictable, beneficial outcomes in human patients

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Fluticasone inhaled is a widely prescribed corticosteroid that helps reduce inflammation in the airways, making it easier to breathe for people with asthma or chronic obstructive pulmonary disease (COPD)

In preclinical models, MOTS-c has also been shown to help cells tolerate metabolic and oxidative stress, which is part of the basis for interest in its potential role in aging and age-related disease

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