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Methods This meta-analysis was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines [10] and has been registered at PROSPERO (CRD42025638461)

It produces a unique protein called ClpB, which behaves as a biological mimetic of alpha-MSH

Their key ingredients, semaglutide and tirzepatide, respectively, are FDA approved for weight loss under the brand names Wegovy and Zepbound

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The labeling for phentermine also contains a candid statement rarely quoted: the limited usefulness of agents of this class should be measured against possible risk factors inherent in their use

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