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However, experts quoted in a July 29 PBS article warned that these supplements do not come close to matching the effectiveness of real GLP-1 agonists such as semaglutide (sold under the brand names Ozempic and Wegovy) and tirzepatide (sold as Mounjaro and Zepbound)

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Antidiabetic agents appear safe and well tolerated in the treatment of an acute depressive episode, but only subgroup analyses of the pooled estimates for depression rating scale scores, response rate and remission rate among depressed patients suggest a possible benefit from an antidiabetic medication for depressive symptoms [165]

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Spiking demand can also make it difficult for many patients to find the branded treatments