These compounds are identified as 4-hydroxyacetophenone (4-HAP), epicatechin-(4,8)-epicatechingallate (B2-3-O-gallate), red Sedum and p -tyrosol used mass spectrometry and nuclear magnetic resonance spectroscopy ( 2-[4-Alkoxy-3-(1H-tetrazol-1-yl)phenyl]-6-oxo-1,6-dihydropyrimidine-5-carboxylic Acid Derivatives The researchers in this study designed and synthesized a series of 2-[4-alkoxy-3-(1H-tetrazol-1-yl)phenyl]-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives (8a-8z) and further evaluated their inhibitory effect on xanthine oxidase in vitro (Zhang et al., 2019)
doi:10.1016/j.neuroscience.2009.08.026 78
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However, evidence of the efficacy of enhanced control of glycemia in preventing neuropathy is stronger in patients with type 1 diabetes than in those with type 2 diabetes (73)
