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Features associated with poor prognosis include a large primary tumor (over 5 cm across), high grade disease, co-existent neurofibromatosis, and the presence of metastases

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Richardson et al., 2020)

For example, whereas sulphide-oxidising activity is virtually undetectable in nervous system cells, colonocytes display high expression and activity of SOP enzymes, 131,132,133 consistent with the high H 2 S concentrations that result from gut microbial metabolism

Reset Method For patients with knee arthritis, meniscus or ligament tears, bone-on-bone joints, and chronic knee pain