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CIRS vs Mycotoxin Illness CIRS: Broad biomarker dysregulation Persistent innate immune activation Non-CIRS Mycotoxin Illness: Selective biomarker abnormalities May include immune sensitization without full systemic dysregulation This patients profile aligned with the latter

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The Canadian CT Head Rule, Sakamoto notes, was created to identify patients at risk of neurosurgical intervention and clinically important brain injury while safely reducing unnecessary CT use. It was intended for patients with a minor head injury (Glasgow Coma Scale 13-15) who had a loss of consciousness (that was witnessed), amnesia, or disorientation

Metabolic stress promotes the formation of advanced glycation end products (AGEs), which activate inflammatory signaling through the receptor for advanced glycation end products (RAGE) [8]