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Many patients can lose more weight following bariatric surgery than with medications, in part because the surgery makes an anatomical change

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It is commonly used to support fat loss and reduce cravings as part of a structured weight loss program

Patients require evaluation before starting DMARDs to rule out contraindications to the medications (meaning the patient should not take a certain medication due to the harm it would cause) and monitoring while using them to watch for serious side effects

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These drugs generated sales of $13.5 billion and $4.4 billion, respectively, in 2023