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Liu X, Zhao J, Liu F, Xie Z, Lei X, Wang Z, et al

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While lipid-based nanoparticles (LNPs) have garnered significant clinical traction, evidenced by their successful deployment in mRNA vaccines and offering promise for challenging therapeutics like PROTACs (Table 2) [209, 210], the path to clinical translation for nanocarrier-based PROTAC delivery is fraught with hurdles