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Thus residues Glu16, Glu17, Arg20, Glu24, and Lys27 define the hydrophilic face of the peptidic drug

p , GGsTop aliquots (25 mg/mL in H 2 O) were kept at room temperature for the indicated number of days, after which their inhibitory potency was assessed using an in vitro activity assay with mouse kidney lysates (n = 3 technical replicates)

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233 Transplanting the gut microbiota of elderly mice into young mice can lead to loss of intestinal wall integrity in young mice, thereby promoting the release of microbiota metabolites into the circulatory system, leading to inflammation of the brain and eyes

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