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Orforglipron (Eli Lilly): A small-molecule oral GLP-1 receptor agonist
[1] Other safety considerations include risk of gallbladder disease, pancreatitis, diabetic retinopathy complications (particularly with rapid A1c reduction), and hypersensitivity reactions
GLP-1 and GIP receptors are widespread in humans with abundant levels in pancreatic beta and, to a lesser degree, alpha cells
Anything outside that range isn't necessarily wrong, but it's worth examining dose, baseline body composition, and starting point