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Early initiation of metformin treatment plus an SGLT-2 inhibitor is recommended in most people with type 2 diabetes, followed by the addition of glucose-lowering agents as needed to achieve individualised glycaemic targets (Table 2)

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It can lead to death, which is why patients are typically asked to fast before surgery

Emadi A, Burns KH, Confer B, Borowitz MJ, Streiff MB (2008) Hematological manifestations of nephropathic cystinosis