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Temperature excursions above 8C cause irreversible peptide bond hydrolysis and loss of receptor affinity

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A secondary analysis from fecal samples collected from these volunteers identified Bacteroides ovatus and Phocaeicola dorei , which positively correlated with unconjugated BAs, and Bifidobacterium adolescentis, Collinsella aerofaciens , and Faecalibacterium prausnitzii , which positively correlated with secondary BAs, as the bacterial species candidates that affected gut BA metabolism (187)

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