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British Association of Dermatologists living guideline for managing alopecia areata

It is comparable to a duodenal switch, a complex bariatric surgery that reduces stomach size and reroutes the small intestine

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Stopping treatment without maintaining lifestyle changes may lead to gradual weight regain

[246] showed that Nrf2 inhibition increased oxidative stress and aggravated hypertension in mice, whereas Nrf2 activation alleviated hypertension during Ang II infusion, highlighting its therapeutic relevance.Mitochondrial dysfunction, including impaired energy metabolism, increased mtROS, and mtDNA damage, amplifies ferroptosis and worsens endothelial injury [247, 248]