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This oxidative crisis leads to red blood cell destruction, a key concern in malaria treatment and CSIR NET life sciences exams. Primaquine Mechanism in Hemolysis Primaquine treats Plasmodium vivax relapses but its quinone metabolites like 5,6-POQ generate ROS, oxidizing hemoglobin and GSH

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doi: 10.2147/COPD.S135338 124 MaguireJ

disruption of pathways necessary for adequate cell regeneration and ATP production facilitates serum phosphate levels remaining high, with some researchers postulating an association of this with increased mortality

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