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Physiological Reviews, 82(1), 47-95

Sun et al., 2016)

Nonarteritic anterior ischemic optic neuropathy (NAION) , a rare but serious condition that affects the optic nerve and can cause permanent vision loss NAION is a leading cause of sudden, painless loss of vision in one eye, often described as an eye stroke. It affects up to 1 in 10,000 people

Values below 3% are not shown on graphs to improve readability

Wide variation by country: The UK and Canada have the lowest drug shares (9% and 11%), while Japan and South Korea report the highest at about 20%

Mechanism-based concepts of size and maturity in pharmacokinetics