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This degradation compromises the molecular integrity of the active ingredient, potentially resulting in diminished glycaemic control

Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation, which typically diminish over time with dose titration

Subcutaneous GLP-1 injections in the arm are a common self-administration route, though the abdomen and thigh remain preferred sites due to blood flow patterns

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In addition, the brain is susceptible to oxidative stress because its high in fat, which can oxidize or go rancid. The brain is also high in iron and zinc, which can further fuel oxidative stress