PT-141 can raise systolic blood pressure by somewhere around 6 to 12 points for a period of time
Giorgi C, Marchi S, Simoes ICM, Ren Z, Morciano G, Perrone M, et al
These risks are heightened when kratom is combined with other substances or used in high doses
Again, we still need more research because its a small study
Standard RDA: 2.4 mcg for adults Senior-Specific Needs: Often higher than 2.4 mcg due to absorption issues Recommended Intake for Seniors: At least 2.4 mcg, potentially much higher with supplementation Why the Standard 2.4 mcg May Not Be Sufficient The standard 2.4 mcg dosage might not be enough for seniors for a few reasons: Decreased Stomach Acid: Needed for B12 release from food Atrophic Gastritis: A common condition in older adults that makes it hard to absorb B12 Medication Interference: Some medicines can also block B12 absorption For those over 50, its best to get most of their vitamin B12 from supplements and fortified foods
Hockey_player yes this is the entereohepatic recirculation, which is broken in PA due to lack of intrinsic factor
