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Do I have any personal health history factors that would change the standard risk-benefit calculation - cardiovascular history, blood clot history, cancer history

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There is also the question of what happens when the medication is stopped, whether cravings and compulsive behaviours return, which remains unanswered

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Medullary thyroid carcinoma (a rare thyroid cancer) is a known contraindication to GLP-1 agonists based on animal study data, so if you have personal or family history of medullary thyroid cancer or MEN2 syndrome, GLP-1 therapy is not appropriate for you