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Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells

By conducting RNA-seq analysis, SOD activity and malondialdehyde assays in ovaries, as well as ROS staining in oocytes, we revealed that the semaglutide treatment reduced the elevated oxidative stress in ovaries and high ROS levels in oocytes from PPO mice, possibly through activating the PI3K/AKT pathway and improving the state of SOD

The processes leading to increased arterial stiffness are related to structural remodelling such as increased collagen and decreased elastin in the vessel wall, as well as higher resting vascular tone, endothelial dysfunction, and reduced nitric oxide bioavailability (Lyle and Raaz, 2017)

26 The first stage of medication processingreceiving a prescriptioncreates a significant risk for errors

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doi: 10.1016/0014-2999(85)90249-3